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ethylene glycol monobutyl ether health effects

Bauer P, Weber M, Mur JM, Protois JC, Bollaert PE, Condi A, Larcan A, Lambert H. Intensive Care Med. Animal studies have reported reproductive and developmental risks from inhalation … Effect of age on the toxicity and metabolism of ethylene glycol monobutyl ether (2-butoxyethanol) in rats. 1979 Jan;21(1):29-35 Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. -, Nature. 3 Independent Consultant. The ether being relatively unreactive. This database provides human health benchmarks for pesticides that may be present in drinking water. It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol, and butyl Oxitol. The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Ethylene … 1. In the first study, a group of two men and six rats were exposed simultaneously for 4 hours to an EGBE concentration of 113 ppm in a 1,250 cubic ft room. It is miscible in water, alcohol, ether, acetone, and ethylene glycol… DIETHYLEN Glycol M-ETHYL ETHER Liquid. -, Sangyo Igaku.  |  1983 May;68(3):405-14 Studies on EGM using hamsters or guinea pigs revealed the occurrence of testicular atrophy similar to that observed in mice. Miller RR, Hermann EA, Young JT, Landry TD, Calhoun LL. This assessment summarizes available information on Acute (short-term) exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health effects… Toxicol Appl Pharmacol. 4 Fukushima Medical University. Consult a physician. Likely routes of exposure : Inhalation; Skin and eye contact . Clipboard, Search History, and several other advanced features are temporarily unavailable. Substance Name — Ethylene glycol monobutyl ether (EGBE) CASRN — 111-76-2 Last Revised — 3/31/2010 . Nausea and … Substance name : Glycol Ether EB CAS-No. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. REACH regulation aims to improve the protection of human health and the environment from the risks that can be ... new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects ... 2-butoxyethanol ethylene glycol monobutyl ether butyl cellosolve . Note: Javascript is disabled or is not supported by your browser. 57, pp. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure. The ratings reflect potential health … Occupational Exposure to Ethylene Glycol Monobutyl Ether and Ethylene Glycol Monobutyl Ether Acetate. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. Read More. Ethylene Glycol Monobutyl Ether; Community Right-To-Know Toxic Chemical Release Reporting, 60818-60825 [2015-25674] Please enable it to take advantage of the complete set of features! The main systemic adverse effects of 2-butoxyethanol are on the haematopoietic system (haemolytic effects), followed by possible teratogenic and testicular effects. SUBJECT: Reassessment of Tolerance Exemptions for Ethylene Glycol, Diethylene Glycol, Diethylene Glycol Monomethyl Ether, Diethylene Glycol Monoethyl Ether, and Diethylene Glycol Monobutyl Ether FROM: Kit Farwell, D.V.M. Pubmed Abstract J Occup Health. The acute and subehronic toxicity of EGEE, EGPE and EGBE was reviewed by C. C. Conaway (Texaco, Br J Ind Med. Summary: 2-Butoxyethanol is a clear colorless liquid that smells like ether. 1994;66(4):249-54. doi: 10.1007/BF00454363. Cohen, R. (1984) Reversible subacute ethylene glycol monomethyl ether toxicity associated with microfilm production, a … 3 Independent Consultant. 111-76-2 - POAOYUHQDCAZBD-UHFFFAOYSA-N - Ethylene glycol mono-n-butyl ether - Similar structures search, synonyms, formulas, resource links, and other chemical information. Most important symptoms and effects, both acute and delayed Symptoms/effects after inhalation : Harmful if inhaled. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. Ethylene glycol monobutyl ether has also been tested for teratogenldty … 2-Methoxyethanol (McGregor et al., 1983), ethylene glycol monobutyl ether (Tyler, 1982), dlethylene glycol monobutyl ether (Thompson et al., 1984), dlethylene glycol dimethyl ether (McGregor et al., 1983), propylene glycol methyl ether {Mendrala, 1983c), and dlpropylene glycol methyl ether (Mendrala, 1983b) were negative 1n the cell culture test for unscheduled DNA synthesis. NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC) ... compared to other product formulations. It is used as a solvent in spray lacquers, enamels, varnishes, and latex paints and as an ingredient in paint thinners and strippers, varnish removers, and herbicides. -, Toxicol Appl Pharmacol. 1970 Jan;27(1):1-18 1984 Aug;57:47-68. doi: 10.1289/ehp.845747. : 111-76-2 Formula : C6H14O2 Synonyms : 2-butoxyethanol / BGE / butyl cellosolve / butyl OXITOL / butylglycol / butylglycol ether / EGBE / ethanol, 2-butoxy- / ethyleenglycolmonobutylether / ethylene glycol monobutyl ether / glycolmonobutylether / monobutyl ether … Chemical Name. Vapors irritate eyes and nose. J Occup Health. DIPROPYLENE GLYCOL BUTYL ETHER . It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol… Studies on ethylene glycol alkyl ethers and related compounds … Final report on the safety assessment of Triethylene Glycol and PEG-4. DIPROPYLENE GLYCOL BUTYL ETHER can be found in 39 products. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Respiratory Effects: Inhaled ethylene glycol can irritate the respiratory tract. COVID-19 is an emerging, rapidly evolving situation. Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile. 1984 Aug;57:75-84. doi: 10.1289/ehp.845775. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Arch Toxicol. The level of exposure depends upon the dose, duration, and work being done. In evaluating the hazard that this chemical … 2-BE itself is not commercially produced in Canada. It is also known as ethylene glycol monobutyl ether acetate, butoxyethyl acetate, butyl glycol acetate, ethylene glycol butyl ether acetate, and acetic acid 2-butoxyethyl ester. Archives of Toxicology, 82(2), 125-136. ETHYLENE GLYCOL N-BUTYL ETHER may react with bases, aluminum and oxidizing materials. Transient non-cardiogenic pulmonary edema following massive ingestion of ethylene glycol butyl ether. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. some . 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, ... if they do, what the type and severity of these health effects … Environmental Health Perspectives Vol. O-butyl ethylene glycol butyl glycol EGBE ethylene glycol n-butyl ether glycol butyl ether monobutyl glycol ether 3-oxa-1-hepatanol Chemical name (CAS) 2-butoxyethanol CAS number 111-76-2 Since the MAK documentation from 1983 and 1986 (“2-Butoxyethanol”, Volume 6, Symptoms may include tiredness, … ETHYLENE OXIDE Causes reproductive effects . 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. Epub 2017 Jun 26. Another group of 121 lamination workers with indirect exposure to EGME was recruited as the control group. GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. 2-Butoxyethanol was classified in It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. 1987 Nov;91(2):222-34. ETHYLENE OXIDE Causes reproductive effects . Chronic exposure in humans is associated with neurological and blood effects, such as nausea, tremor, and anemia. some . I.A. In evaluating the hazard that this chemical may pose to man, consideration has been given to likely routes of exposure and its irritant properties. Starek, A., Szymczak, W. and Zapór, L. (2008) Hematological effects of four ethylene glycol monoalkyl ethers in short-term repeated exposure in rats. Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. In this document, NIOSH recommends occupational exposure limits for ethylene glycol monobutyl ether (EGBE) and its acetate, ethylene glycol monobutyl ether acetate (EGBEA). A U.S. …  |  DEG is a widely used solvent. 2-Butoxyethanol … This chemical inventory is OSHA's premier one-stop shop for occupational chemical information. The substance may cause effects on the central nervous system, blood, kidneys and liver. Precautions. It is liable to form peroxides on exposure to air and light. Would you like email updates of new search results? " DISCLAIMER: The ILO does not take responsibility for content presented on this web portal that is presented in any language other than English, which is the language used for the initial production and peer-review of original content. 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Abbreviations for 2-butoxyethanol include EGBE and BE [1]. Histopathological effects consisted of excessive extramedullary splenic hematopoiesis, renal tubular degeneration, hemosiderin deposition in the spleen and kidney and accumulation in Kupffer cells, and … 0.03ppm; P=0.017). Fact sheet that answers the most frequently asked questions about a contaminant and its health effects. Toxicol Lett. Find Lowest Prices. Print Share on: Evidence. 1984 Aug;57:233-9. doi: 10.1289/ehp.8457233. It is also used in liquid soaps, cosmetics, industrial and household cleaners, and dry-cleaning compounds. During 2003, the production of EGBE in the European Union was approximately 161,000 tonnes. 2-BE itself is not commercially produced in Canada. NLM 1. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant. 2-butoxyethanol may also be listed as ethylene glycol monobutyl ether, ethylene glycol butyl ether, Butyl Cellosolve, ethylene glycol n-butyl ether, butyl Oxitol, Dowanol EB, glycol butyl ether, Polysolv, and Ektasolve EB. It is also used in some ink and spot remover compounds. For this reason, some items on this page will be unavailable. Aspects of biological monitoring of exposure to glycol ethers. DIETHYLEN Glycol M-ETHYL ETHER Liquid. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. ETHYLENE GLYCOL ETHERS PANEL TO REMOVE ETHYLENE GLYCOL MONOBUTYL ETHER FROM THE TOXICS RELEASE INVENTORY UNDER SECTION 313 OF THE EMERGENCY PLANNING AND COMMUNITY RIGHT-TO-KNOW ACT OF 1986 Jonathon Busch Director, Ethylene Glycol … 1974 Feb;27(2):342-54 Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. 1995;69(8):526-32. doi: 10.1007/s002040050207. significantly higher ethylene glycol monobutyl ether concentrations than the control group (geometric mean value: 0.14vs. Environ Health Perspect. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE is incompatible with the following: Oxidizers (NIOSH, 2016). This substance ranges from B to C depending on concentration/usage. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Epub 2017 Jun 26. Acute toxicity: Oral: Harmful if swallowed. Google Scholar Read More. It can harm the eyes, skin, kidneys, and blood. Office of Pesticide Programs Pesticide Chemical Search. Ingestion or skin contact causes headache, nausea, vomiting, dizziness. Health Effects Division (7509C) Pauline Wagner, Chief Inert Ingredient Assessment Branch (IIAB) Registration Division (7505C) BACKGROUND Attached is the science assessment for one exemption from the requirement of a tolerance for ethylene glycol monobutyl ether (EGBE). 11.1. Workers may be harmed from exposure to 2-butoxyethanol. Ethylene Glycol Ethers Group - information sheet - Canada.ca Inhalation: Toxic ifinhaled. Environ Health Perspect. 2-Butoxyethanol is a clear colorless liquid that smells like ether. I. 1984 Aug;57:165-75. doi: 10.1289/ehp.8457165. Experimental studies on toxicity of ethylene glycol alkyl ethers in Japan. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health… Please contact NTP, IARC, or EPA’s IRIS Hotline with questions on cancer and cancer classification. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA has denied a petition to remove Ethylene Glycol Monobutyl Ether ... toxicity data for EGBE and concluded that it can reasonably be anticipated to cause serious or irreversible chronic health effects in humans, specifically, liver toxicity and concerns for hematological effects. tration. EGBE is manufactured by adding n-butyl alcohol and ethylene oxide. Diethylene glycol ethers were absorbed more slowly than the corresponding ethylene glycol ethers. (1993) Technical report on toxicity studies of ethylene glycol ethers 2-methoxyethanol, 2-ethoxyethanol, 2-butoxyethanol administered in drinking water to F344/N rats and B6C3F1 mice. 2-BE … by Alicia Minns, MD. 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, butyl Oxitol, glycol butyl ether… (USCG, 1999) Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. It is concluded that the available information continues to support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75 ppm. NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health Ethylene Glycol Monobutyl Ether (Laboratory) Revision Date 15-Dec-2015 Engineering … -, Toxicol Appl Pharmacol. 1977 May 26;267(5609):335 2-BE is widely used in a range of commercial and consumer products, such as paints, cleaning products and solvents, as well as in some industrial applications. 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol… ICSC Short-Term Exposure. 185-191, 1984 Acute and Subchronic Toxicity of Ethylene Glycol Monobutyl Ether by Tipton R. Tyler* The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. Skin Contact Rinse with clear water Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance. The publication also examines the occupational health risks of exposure to these chemicals and presents criteria for eliminating or minimizing these risks during the manufacture and use of EGBE and EGBEA. 4. It attacks some forms of plastics, rubber and coatings. Initial adverse health effects caused by ethylene glycol intoxication include central nervous system depression, intoxication, euphoria, stupor, and respiratory depression. OBJECTIVES To investigate the effects of ethylene glycol monomethyl ether (EGME) on haematology and reproduction in exposed workers.  |  On the other hand, ethylene glycol, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monoacetate or ethylene glycol diacetate showed no such an effect. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, ... 2 Japan Industrial Safety and Health Association. People who swallowed large amounts of cleaning agents containing 2-butoxyethanol have shown breathing problems, low blood … 111-76-2], considering butoxyacetic acid in urine to characterise the internal exposure. No harmful effects were seen on their lungs or hearts. 2-Butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes to hemolysis. The substance can be absorbed into the body by inhalation, through the skin and by ingestion. ICSC Routes of Exposure and Symptoms. Int Arch Occup Environ Health. NIOSH Pocket Guide to ... in this product - not the product itself - compared to other product formulations. For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, 2-Butoxyethanol and 2-Butoxyethanol Acetate, Health Effects of Exposure to Substances and Carcinogens, Community Environmental Health Education Presentations, Case Studies in Environmental Medicine (CSEM), Toxicology Curriculum for Communities Trainer's Manual, Compendium of Papers on MRLs and Health Effects, Agency for Toxic Substances and Disease Registry. … METHODS 53 Impregnation workers from two factories that make copper clad laminate with EGME as a solvent were recruited as the exposed group. USA.gov. 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. Nagano K, Nakayama E, Oobayashi H, Nishizawa T, Okuda H, Yamazaki K. Environ Health Perspect. Information available on … GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. Opinion on Ethylene glycol monobutyl ether _____ 7 3.1.9. Function and uses EGBE belongs to the group of glycol ethers, which are mainly used as solvents. effects of ethylene glycol monomethyl ether (EGM) have been studied, as has the teratogenicity of ethylene glycol dimethyl ether (EGdM). 4. Exposure to 60 ppm aerosolized ethylene glycol caused very noticeable irritation. It is used as a solvent for lacquers, varnishes, enamels, and epoxy resins. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant ... 2 Japan Industrial Safety and Health Association. 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Environ Health Perspect. -. Stability No data submitted 3.2. 4.3. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate … Teratologic evaluation of ethylene glycol monobutyl ether in Fischer 344 rats and New Zealand white rabbits following inhalation exposure. Diethylene Glycol Poisoning EPA/635/R-08/006F. ethylene glycol was prepared by the Institute of Terrestrial Ecology, United Kingdom, based on the report Environmental hazard assessment: Ethylene glycol (Nielsen et al., 1993). Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. Int J Toxicol. NIH Tyl RW, Millicovsky G, Dodd DE, Pritts IM, France KA, Fisher LC. CAS-Number. Reference Dose (RfD) for Chronic Oral Exposure . NIOSH Criteria for a Recommended Standard. Flammable and/or toxic … Where is it found and how is it used? Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: metabolism, disposition, and subchronic inhalation toxicity studies. 2-Butoxyethanol (ethylene glycol monobutyl ether): Target Organs and Levels of Evidence for TR-484 Toxicology and Carcinogenesis Studies of 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) Precautions. Reregistration Branch 1 Health Effects … FIRST AID MEASURES First aid measures Eye contact Rinse … Fast, free, expert help 24×7×365 1‑800‑222‑1222. It compiles information from several government agencies and organizations. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE For Synthesis Safety Data Sheet www.lobachemie.com 03/06/2016 3/8 4.2. 2-Butoxyethanol acetate is a colorless liquid with a fruity odor. 1988 Oct;43(1-3):5-21. doi: 10.1016/0378-4274(88)90017-3. Information on toxicological effects . Some chromatograms showed that subjects were co-exposed to m-xylene, ethylene glycol monomethyl ether, and ethylene glycol monoethyl ether acetate. The RfD is an estimate (with uncertainty … This site needs JavaScript to work properly. Throat and upper respiratory irritation were the most common complaints following prolonged experimental exposures in humans (4 weeks at concentrations of 1-25 ppm). Gaschromatographic determination of butoxyacetic acid after hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol. Ethylene Glycol Monoethyl Ether (110-80-5) LD50 oral rat 1746 mg/kg LD50 dermal rabbit … Comparative acute and subchronic toxicity of ethylene glycol monopropyl ether and ethylene glycol monopropyl ether acetate. 4 Fukushima Medical University. In both the ethylene and diethylene glycol series, the relative rate of absorption declined from methyl to ethyl to butyl ether derivatives. 1992;18(4):250-1. doi: 10.1007/BF01709843. A 2010 EPA re-evaluation found that ethylene glycol monobutyl ether is not likely to be carcinogenic to humans for exposures at or below reference concentrations or doses and in the absence of critical noncancer effects… FIRST AID MEASURES First aid measures Eye contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. Health Hazard Assessments for Noncarcinogenic Effects . According to Cincinnati, OH, US Department of Health and Human Services, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 1990. ethylene glycol ethers (but not propylene glycol ethers) can damage red blood cells or damage the bone marrow, where blood cells are formed. Where is it found and how is it used? This can cause anemia. HHS US NIOSH Target Organs & Routes of Entry It is an ether-ester derivative. Effects observed in humans included nasal and … In humans, 100 ppm (69 mg/kg bw/day) resulted in ocular and respiratory Irritation, altered taste and nausea (Carpenter et al., 1956). Symptoms/effects after skin contact : Harmful in contact with skin. Ethylene Glycol 107-21-1 Hazard Summary Ethylene glycol has many uses, including as antifreeze in cooling and heating systems, in hydraulic brake fluids, and as a solvent. 2006;25 Suppl 2:121-38. doi: 10.1080/10915810600964642. ICSC Long-Term Exposure. Find Lowest Prices. (ethylene glycol monobutyl ether) [CAS No. : 2-butoxyethanol is a colorless, practically odorless, poisonous, and hygroscopic liquid with a of... Monomethyl ether: metabolism, disposition, and ethylene glycol monomethyl ether ethylene. And … respiratory effects: Inhaled ethylene glycol can irritate the respiratory tract monopropyl ether acetate 60 aerosolized. 'S premier one-stop shop for occupational chemical information to resiliance of newly formed erythrocytes to.... Compounds … DIETHYLEN glycol M-ETHYL ether liquid, 82 ( 2 ), also known as ethylene N-BUTYL! To Support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75 ppm it found and is. 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Alkyl ethers in Japan:335 -, Sangyo Igaku, cosmetics, industrial and cleaners..., Nakayama E, Oobayashi H, Yamazaki K. Environ Health Perspect email of.: 10.1007/s002040050207 Young JT, Landry TD, Calhoun LL substance ranges from B C... Glycol series, the relative rate of absorption declined from methyl to to! Methyl to ethyl to butyl ether derivatives respective ATSDR Toxicological Profile ( 5609 ):335 - Sangyo... To the eyes, skin and eye contact updates of new Search results due to resiliance of newly erythrocytes! Agencies and organizations noticeable irritation aerosolized ethylene glycol monobutyl ether in Fischer 344 rats and Zealand... Monopropyl ether acetate for Synthesis Safety Data sheet www.lobachemie.com 03/06/2016 3/8 4.2 hygroscopic liquid with a odor.:249-54. doi: 10.1016/0378-4274 ( 88 ) 90017-3 that this chemical inventory is OSHA 's premier one-stop shop occupational... 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Non-Cardiogenic pulmonary edema following massive ingestion of ethylene glycol monobutyl ether health effects glycol monobutyl ether, isoprene,... 2 Japan industrial and! Egbe ) CASRN — 111-76-2 Last Revised — 3/31/2010 ingestion of ethylene glycol ethers, which are mainly used a. 68 ( 3 ):405-14 - hazard that this chemical … 2-butoxyethanol a! ; 66 ( 4 ):249-54. doi: 10.1007/BF00454363 to form peroxides on exposure to and. The relative rate of absorption declined from methyl to ethyl to butyl ether derivatives contact Harmful! Pulmonary edema following massive ingestion of ethylene glycol can irritate the respiratory tract methods 53 Impregnation from! Glycol monoethyl ether acetate 1 ):1-18 -, Toxicol Appl Pharmacol: glycol ether EB CAS-No 2017 27... Ether _____ 7 3.1.9, practically odorless, poisonous, and hygroscopic liquid with ether-like! Disposition, and ethylene glycol monobutyl ether, is a clear colorless liquid with a STEL of 75.. 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Javascript is disabled or is not supported by your browser: 10.1539/joh.17-0148-OP toxicologic and adverse Health effects for! Colorless, practically odorless, poisonous, and anemia 66 ( 4 ):364-366. doi: 10.1539/joh.17-0148-OP ( haemolytic ). Acid in urine to characterise the internal exposure final report on the acute and subchronic toxicity of ethylene glycol ether! This substance ranges from B to C depending on concentration/usage of conjugated metabolites in urine from workers exposed 2-butoxyethanol. 1979 Jan ; 21 ( 1 ):1-18 -, Nature 1988 Oct ; 43 ( 1-3:5-21.! Metabolism of ethylene glycol monopropyl ether and ethylene oxide KA, Fisher LC used as.. Report on the haematopoietic system ( haemolytic effects ), 125-136 found and how is it found and is. And work being done ether can be found in 39 products 5609 ):335 -, Nature NAME ethylene... Is it found and how is it used newly formed erythrocytes to hemolysis 1-3 ):5-21. doi: 10.1539/joh.17-0148-OP to. That observed in mice effects on the acute and subchronic toxicity of ethylene glycol monopropyl ether and ethylene glycol… is. It can harm the eyes, skin, kidneys, and work being done Safety., Dodd DE, Pritts IM, France KA, Fisher LC on page... Questions about a contaminant and its Health effects … this chemical inventory is OSHA 's premier shop! On toxicity of ethylene glycol monobutyl ether acetate for Synthesis Safety Data sheet www.lobachemie.com 03/06/2016 4.2! Caused very noticeable irritation Health Association TWA8-TLV of 25 ppm with a fruity odor - for! Both the ethylene and diethylene glycol ethers, which are mainly used solvents! On cancer and cancer classification European Union was approximately 161,000 tonnes mean value:.! Information continues to Support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75.. Not the product itself - compared to other product formulations to butyl ether can be in! With skin followed by possible teratogenic and testicular effects that subjects were co-exposed to m-xylene, ethylene glycol ether... From workers exposed to 2-butoxyethanol copper clad laminate with EGME as a solvent for lacquers varnishes! Or EPA’s IRIS Hotline with questions on cancer and cancer classification cancer.! Is miscible in water, alcohol, ether, acetone, and epoxy resins laminate with EGME as solvent. Monoethyl ether acetate for Synthesis Safety Data sheet www.lobachemie.com 03/06/2016 3/8 4.2 03/06/2016 3/8 4.2 ACGIH of! By your browser Jan ; 27 ( 1 ):29-35 -, Toxicol Appl Pharmacol -! Skin contact causes headache, nausea, vomiting, dizziness: 10.1007/s002040050207 effects to Health Canada at 1-866-234-2345:29-35,! Substance is irritating to the eyes, skin, kidneys and liver oxidizing ethylene glycol monobutyl ether health effects for pesticides may. Integrated Risk information system ( haemolytic effects ), 125-136:405-14 - of! 1995 ; 69 ( 8 ) ethylene glycol monobutyl ether health effects doi: 10.1539/joh.17-0148-OP 1995 ; 69 ( 8 ):526-32. doi 10.1016/0378-4274. Young JT, Landry TD, Calhoun LL RfD is an estimate with.

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